I've always wondered why the different standard of drug prices in the different cities? CH/DT prices can go somewhat higher than the east and west coast cities.

CH and DT also have the advantage of shorter flight times between the east and west coast, whereas being on either side of the country can mean it will take you a long while to get back to your home city, hence why a lot of power plays are made and we see people heading to the central cities and setting up shop.

Now if the other cities had something unique about them I'd understand why the low prices, I mean for example maybe if say LV had casino's running out there like we saw in the past I could get on board with the idea that the drugs cost less there due to there being another source of income to tap into, but as it is I just don't understand why the drug prices are different. If anything I'd suggest the prices are reversed in order to get a better spread around the cities.

I think if you want people to spread out and make the most of each of the cities then this is something that should probably be looked at. Personally I've always felt that LA/LV were a bit of a joke city. Usually we see NY, PH, CH, DT occupied and the west coast left alone, right now that isn't the case but the east and west cities have always been cities that I've never really bothered with unless I've had a crew there as it's more profitable to slip in between CH and DT, I know this is the case for a lot of others too.

Honestly, I like the idea of giving each City it's own worth. So every City has it's own reason to be lived in/visited (whether it be better prices, cheaper gambling, whatever it may be). However, I don't think what you've suggested would help. I think this is something that needs a lot of thought, balancing and refining before it could be released properly.

As of right now, my only suggestion is to balance the drug prices to encourage a spread of people across the cities.

I travel from city to city based on the current drug system. I find that I travel more based on that.